Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging
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منابع مشابه
Analysis of the Trypanosoma brucei cell cycle by quantitative DAPI imaging.
Trypanosoma brucei has two DNA compartments: the nucleus and the kinetoplast. DNA replication of these two compartments only partially coincides. Woodward and Gull [Woodward R, Gull K. Timing of nuclear and kinetoplast DNA replication and early morphological events in the cell cycle of Trypanosoma brucei. J Cell Sci 1990;95:49-57] comprehensively studied the relative timing of the replication a...
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Progression of the eukaryotic cell cycle requires the regulation of hundreds of genes to ensure that they are expressed at the required times. Integral to cell cycle progression in yeast and animal cells are temporally controlled, progressive waves of transcription mediated by cell cycle-regulated transcription factors. However, in the kinetoplastids, a group of early-branching eukaryotes inclu...
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I . Hayes, J. I). & Wolf. C. R. ( IYSX) in Ghituthione (’onjugation (Sies, H. & Ketterer. 8.. eds), pp. 315-355. Academic Press Limited, London 2. Meister. A. ( 1980) in Ghrtrithione: Chemicul, Biochemical, mid Medical Aspc~rts (Dolphin, D.. Poulson. R. & Avramovic, 0.. A), pp. 307-474, John Wiley & Sons. New York 3. Kramer, R. A,, Zakher, J. & Kim, G. (1988) Science 241, 604-696 -1. Riirlamh. ...
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The mitochondrial DNA of Trypanosoma brucei is organized in a complex structure called the kinetoplast. In this study, we define the complete kinetoplast duplication cycle in T. brucei based on three-dimensional reconstructions from serial-section electron micrographs. This structural model was enhanced by analyses of the replication process of DNA maxi- and minicircles. Novel insights were obt...
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Trypanosoma brucei provides an excellent system for studies of many aspects of cell biology, including cell structure and morphology, organelle positioning, cell division and protein trafficking. However, the trypanosome has a complex life cycle in which it must adapt either to the mammalian bloodstream or to different compartments within the tsetse fly. These differentiation events require sta...
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ژورنال
عنوان ژورنال: Molecular and Biochemical Parasitology
سال: 2008
ISSN: 0166-6851
DOI: 10.1016/j.molbiopara.2008.04.004